Higher Order Structure

The Higher Order Structure (HOS) Symposium discusses higher order structure as a critical quality attribute for the safety and efficacy of drug products. Protein higher-order structure and dynamics are essential to protein function. HOS can be monitored by a multitude of biophysical and structural characterization tools. The choice of the appropriate biophysical method and the method development and qualification strategies to characterize and control HOS at different stages of the product lifecycle are a matter of interest and debate for a wide range of audiences.

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