Hotel Information

Hilton Orange County/Costa Mesa
3050 Bristol St.
Costa Mesa, California, USA 92626
Telephone: (714) 540-7000

Make Your Hotel Reservations

Join us at the Hilton Orange County/Costa Mesa in Costa Mesa, Southern California, USA for Mass Spec Symposium 2025!

Hilton Orange County/Costa Mesa is the largest hotel in Costa Mesa and is located in the heart of South Coast Metro, Orange County's business district. Enjoy the proximity to the South Coast Plaza Stores, Orange County's premier shopping and dining destination - only 0.2 miles. Experience the spectacular 48,000 sq. ft. of event space - breakout rooms, boardrooms, and ballrooms. Hilton Orange County hotel also features an on-site restaurant, outdoor pool, complimentary fitness and business centers, and beautiful guest rooms.

Reservations
A room block is reserved for Symposium delegates at the special group rate of $185 USD for a *single or double room (plus 11.37% occupancy tax). The deadline to reserve your accommodations will close September 1, 2025. The Hilton Orange County/Costa Mesa requires a credit card to guarantee your reservation. In the event of a cancellation, the hotel requires 72 hours’ notice to receive a full refund.

After September 1, 2025, reservations will be accepted on a space and rate availability basis. We recommend that attendees book their hotel accommodations well before the deadline to secure this rate.

NOTE: Check-in time is 4:00 PM and check-out time is 11:00 AM.

Parking and Transportation

For local attendees that will drive to the Symposium, parking is available on-site for an additional fee. 

Hilton Costa Mesa offers complimentary shuttle to and from John Wayne Airport and within 5 miles of the hotel. Attendees traveling by plane can utilize John Wayne Airport/Orange County (3 miles away), Los Angeles International Airport (36 miles away), or Long Beach Airport (Daugherty Field) (20 miles away). 

By staying at the host hotel, you help CASSS meet its contractual obligations and keep future registration fees reasonable. Please take this into consideration when making your accommodation decisions.

*Room types are not guaranteed and are based on availability when the individual reservation is made.