COVID Protocol

Important Attendee Deadlines
Wednesday, June 25, 2025 | Next-Gen Investigator Awards Application Deadline

Last day to apply for a Next Generation Investigator (NGI) Award. NGI Awards are an excellent opportunity for graduate students, post-doctoral researchers, or early career industrial scientists to meet, network, and participate in exchanging knowledge with industry peers from across the world with waived registration and grants to offset travel expenses.

Learn More About Next-Gen Award     Apply Now for Mass Spec Next-Gen Award

Monday, September 1, 2025 | Hotel Accommodations

Last day to reserve your hotel accommodations at the host hotel at the special group rate. Please note: program registration does not include lodging, so be sure to book your hotel room before the deadline. 

Make Your Hotel Reservations

Wednesday, September 10, 2025 | Registration

Last day to register for your badge. Registration closes at 5 PM Pacific (PDT). 

View Mass Spec Registration Fees 

Hotel Information

Hilton Orange County/Costa Mesa
3050 Bristol St.
Costa Mesa, California, USA 92626
Telephone: (714) 540-7000

Make Your Hotel Reservations

Join us at the Hilton Orange County/Costa Mesa in Costa Mesa, Southern California, USA for Mass Spec Symposium 2025!

Hilton Orange County/Costa Mesa is the largest hotel in Costa Mesa and is located in the heart of South Coast Metro, Orange County's business district. Enjoy the proximity to the South Coast Plaza Stores, Orange County's premier shopping and dining destination - only 0.2 miles. Experience the spectacular 48,000 sq. ft. of event space - breakout rooms, boardrooms, and ballrooms. Hilton Orange County hotel also features an on-site restaurant, outdoor pool, complimentary fitness and business centers, and beautiful guest rooms.

Reservations
A room block is reserved for Symposium delegates at the special group rate of $185 USD for a *single or double room (plus 11.37% occupancy tax). The deadline to reserve your accommodations will close September 1, 2025. The Hilton Orange County/Costa Mesa requires a credit card to guarantee your reservation. In the event of a cancellation, the hotel requires 72 hours’ notice to receive a full refund.

After September 1, 2025, reservations will be accepted on a space and rate availability basis. We recommend that attendees book their hotel accommodations well before the deadline to secure this rate.

NOTE: Check-in time is 4:00 PM and check-out time is 11:00 AM.

Parking and Transportation

For local attendees that will drive to the Symposium, parking is available on-site for an additional fee. 

Hilton Costa Mesa offers complimentary shuttle to and from John Wayne Airport and within 5 miles of the hotel. Attendees traveling by plane can utilize John Wayne Airport/Orange County (3 miles away), Los Angeles International Airport (36 miles away), or Long Beach Airport (Daugherty Field) (20 miles away). 

By staying at the host hotel, you help CASSS meet its contractual obligations and keep future registration fees reasonable. Please take this into consideration when making your accommodation decisions.

*Room types are not guaranteed and are based on availability when the individual reservation is made.

Health and Safety

CASSS is committed to protecting its attendees, participants, and staff members to the highest degree possible when attending our conferences. To ensure we provide a safe environment, CASSS strongly encourages COVID-19 vaccinations, and all other routine vaccinations to protect you from infectious diseases, serious illness, and hospitalization. CASSS will follow guidances established by the facility hosting the conference and/or local and state health authorities in which the conference is located.

For the safety of all attendees, we expect everyone to take everyday preventive actions prior to, and during the conference, to stay safe and healthy. These actions include, but are not limited to:

  • Avoid close contact with people who are sick.
  • If you are sick, limit contact with others as much as possible to keep from infecting them.
  • Cover your nose and mouth with a tissue when you cough or sneeze.
  • Wash your hands often.

Wearing a face mask throughout hotel common space and conference designated areas is recommended but not required.

If you tested positive for COVID-19, have been directly exposed to the virus, or exhibit any symptoms of the COVID-19 virus, you should isolate and not attend the in-person conference.

CASSS will follow local guidelines, including the current measures from the OC Health Care Agency: https://www.ochealthinfo.com/services-programs/disease-prevention/diseases-conditions/covid-19-resources

CASSS is committed to monitoring the local status for in-person conferences and will update our guidelines as necessary. Registrants will be informed about any changes through various communication channels, including email and website, as needed.

If you have any other questions, please contact the CASSS office at 510-428-0740.

Promote Your Participation

We encourage you to promote your participation in the program on social media. Please visit the Mass Spec Social Media Kits and Resources page for customizable images to highlight your role and experiences with the Symposium.

Access Mass Spec Social Media Kits

Be sure to tag CASSS and use #MassSpec2025 in your posts!

Why Attend?

Symposium Overview

The 2025 Mass Spectrometry (Mass Spec) Symposium will bring together industry, academia, and regulatory agencies from around the world to discuss best practices and innovative approaches for mass spectrometry applications in the discovery, development, and commercialization of biopharmaceuticals.

Program Overview

The three-day program features speaker presentations, panel discussions, and poster sessions that give you the opportunity to engage with fellow attendees in meaningful discussions on the latest practices and challenges for mass spectrometry applications in biopharmaceuticals. Be ready to network, collaborate, and expand your knowledge.

2025 Session Topics Include:

  • MAM for Product & Process Characterization & Quality Control
  • Mass Spectrometry in Cell & Gene Therapy
  • Mass Spectrometry in Higher Order Structure
  • Molecular Design, Developability, and Biotransformation
  • MS Trends in Regulatory, Research, Review, and Standard
  • Multispecifics and ADCs Characterization
  • Multi-Omics in Process Development 
  • New Technologies, Approaches, and Methods

Benefits of Attending

  • Hear relevant, timely updates from leading experts in the field.
  • Discuss current and trending topics in the industry.
  • Network with peers from industry, regulatory, academia, consulting, and exhibitors, from entry-level to senior-level, from small companies to government agencies.
  • Connect with a community from around the world.

Attendees in 2024 Included Peers From:

  • Industry
    • AbbVie Inc., Amgen Inc., Biogen, Boehringer Ingelheim Pharmaceuticals, Inc., Bristol-Myers Squibb Company, Eli Lilly and Company, Genentech, a Member of the Roche Group, Merck & Co., Inc., Pfizer, Inc., Regeneron Pharmaceuticals, Sanofi, SCIEX, Thermo Fisher Scientific, Waters Corporation, Roche
  • Regulatory
    • CBER, FDA, CDER, FDA, National Institute for Bioprocessing Research & Training (NIBRT), National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL), National Institute of Standards and Technology (NIST), National Institutes of Health (NIH), US Pharmacopeia
  • Academia
    • Indiana University, University of Maryland, Baltimore County, University of Mississippi, University of Oklahoma, University of Washington, University of Wisconsin, Madison, Washington University in St. Louis

Speakers and Panelists in 2024 Included Experts From:

  • Industry
    • AbbVie Inc., Boehringer Ingelheim Pharmaceuticals, Inc., Bristol-Myers Squibb Company, Genentech, a Member of the Roche Group, Johnson & Johnson, Merck & Co., Inc., Novartis, Pfizer, Inc., Regeneron Pharmaceuticals, Sanofi, Waters Corporation
  • Regulatory
    • CBER, FDA, CDER, FDA, National Institute for Bioprocessing Research & Training (NIBRT), National Institute of Standards and Technology (NIST), National Institutes of Health (NIH), US Pharmacopeia
  • Academia
    • Indiana University, University of Mississippi, University of Oklahoma, University of Washington, University of Wisconsin, Madison, Washington University in St. Louis