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The Netherlands Area Biotech Discussion Group - May 2020
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20 May 2020 (16:00 - 17:30)

Virtual Meeting

Thank you to everyone who joined us for

COVID-19 Vaccine Discovery at Janssen


Lucy Rutten


Danielle van Manen

Janssen Vaccines & Prevention

COVID-19 is an infectious disease caused by SARS-coronavirus 2 (SARS-CoV-2) which attacks the respiratory system. On March 11th COVID-19 was declared a global pandemic having today infected over 4 million people across the world of which more than 290,000 have died. As part of Johnson and Johnson's multi-pronged approach to fight COVID-19, Janssen is developing a vaccine against COVID-19 leveraging our proven AdVac® and PER.C6® platforms. A lead COVID-19 vaccine candidate was identified, and manufacturing for clinical trials has started. The expectation is to initiate human clinical studies of the lead vaccine candidate at the latest by September 2020, with clinical data on safety and efficacy available by the end of the year. This could allow COVID-19 vaccine availability for emergency use in early 2021, a substantially accelerated time frame in comparison to the typical vaccine development process.

Lucy Rutten studied Biomedical Sciences in Leiden. Her major subject was Protein Crystallography. She acquired her PhD and carried out a Veni project at Crystal and Structural Chemistry in Utrecht (from 1997-2007), characterizing several bacterial outer membrane proteins. Subsequently she worked at Structural Neurobiology (KU Leuven), Belgium and for Crossbeta Biosciences in Utrecht, both for a year. She then made a sidestep to select antibodies against HIV using phage display at Biomolecular Imaging (Utrecht University) and QVQ. August 2014, she started working in Leiden for Janssen Vaccines & Prevention, part of Johnson & Johnson where she is leading the HIV-team designing a structure-based vaccine against HIV, which is currently on hold, because she and her team are now fully dedicated to the development of a SARS-CoV-2 vaccine.



20 May 2020
16:00 - 17:30
For more information on upcoming programs, please visit 
the Netherlands Area Biotech (NLab) Discussion Group homepage, 



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