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HOS 2020: Scientific Program
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To view the preliminary program agenda, click here.



Keynote Speakers

SPARK: Translating Academic Discovery to Patients’ Benefit: Lessons from Our 13 Years of SPARK at Stanford and Around the World

Daria Mochly-Rosen, Stanford University

Session Speakers

Probing Protein Unfolded States with Time-resolved FRET, Unnatural Amino Acids, and Microfluidic Mixing 

Osman Bilsel, University of Massachusetts Medical School

Affinity Capture Self-interaction Nanoparticle Spectroscopy (AC-SINS)

Qing Chai, Eli Lilly and Company


Risk-Based Assessment of CQAs for Bispecific Molecules

Dana Filoti, AbbVie Inc.


Backgrounded Membrane Imaging (BMI) for High-Throughput Characterization of Subvisible Particles During Biopharmaceutical Drug Product Development

Constanze Helbig, Coriolis Pharma Research


Structure-based Investigations Related to Decreased Potency in Antibodies Attributed to Alternate Conformations

Nate Joh, Amgen, Inc.


Impact of Immunoglobulin G1 Fc Sialylation on Backbone Amide H/D Exchange

Felix Kuhne, Roche Diagnostics GmbH and University of Muenster


Automated, High-throughput Infrared Spectroscopy for Secondary Structure Analysis of Protein Biopharmaceuticals

Lucy Liu, Pfizer, Inc.


Measuring Enzyme Kinetics, Inhibition, and Allostery Using Isothermal Titration Calorimetry

Anthony Mittermaier, McGill University

Biophysical Assessment of AAV Aggregates

Lake Paul, BioAnalysis, LLC


Five Computational Developability Guidelines for Therapeutic Antibody Profiling

Matthew Raybould, University of Oxford


Collision Induced Unfolding for High-throughput HOS Analyses

Brandon Ruotolo, University of Michigan




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